(Key Laboratory of Advanced Technologies of Materials (MOE), School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China)
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DOI:
10.7502/j.issn.1674-3962.2012.05.04
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Abstract:
The porous scaffold is a key factor in the application of tissue engineering. Porous scaffolds which play the role of extracellular matrix similarly provide space for cell adhesion and the subsequent derivation of cells to organization. At present, although a large number of porous scaffolds have been fabricated by various preparation technologies, preparation technologies and performance optimizations of porous biomaterials scaffolds is still a hot topic in the field of tissue engineering. Combined with the work in our laboratory, this paper reviewed a variety of preparation technologies (including particle accumulation method, fiber accumulation method, foam immersion method, particle leaching method, etc.) of biomaterials scaffolds with various types of porous structure and illustrated the effect on pore structure, connectivity and mechanical property, etc. The aim is to provide a porous biomaterials scaffold to satisfy the need of tissue engineering.