(1 Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China) (2 Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China)
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DOI:
10.7502/j.issn.1674-3962.2012.09.04
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Abstract:
With the development of new technology to treat cardiovascular disease (CVD), cardiovascular stents have drawn more and more attention as one of the most effective device in the treatment of CVD. In this paper, we mainly focused on two types of biodegradable metallic vascular stents which are mostly investigated nowadays,namely magnesium alloy stents and iron based alloy stents. We summarized the research progresses on these biodegradable metallic alloys from the viewpoint of materials science in the present days and the animal experiments, clinic trail results of their stents as well. We overviewed about the finite element design, stress analysis, mechanical property, degradation performance, biocompatibility of the biodegradable metallic stents. Finally, we pointed out the deficiency of current biodegradable metallic stent and their future research direction.