1.Engineer Research Center in Biomaterials, Sichuan Universtiy，Sichuan Chengdu 610064
2.School of chemical engineering, Chongqing Universty of Technology, Chongqing 400054
3. SINOPEC Shengli Oilfield Company Research Institute of Petroleum Engineering, Workover & Completion Research Center, ShanDong Dongying 257000
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DOI:
10.7502/j.issn.1674-3962.2015.03.01
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Abstract:
Gene therapy, as a promising therapeutics to treat genetic or acquired diseases, has received significant attention in the past several decades due to its advantages over traditional therapies. And successful gene therapy was based on high-performance delivery system. Meanwhile, virus-mimic carrier constructed by self-assembly could provide effective strategy and method for gene therapy. In this paper, virus-mimic systems were classified into three different kinds by self-assembly models and the recent progress of various virus-mimic gene carrier systems was summarized.