1.Institute of High Performance Polymers, Qingdao University of Science and Technology, Qingdao 266042,China) （ 2.Institut Europeen des Membranes, UMR CNRS 5635, Universite Montpellier II, Montpellier 34095)
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DOI:
10.7502/j.issn.1674-3962.2016.03.09
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Abstract:
Hydrogels have practical significance and broad application prospects in the field of tissue engineering , biomedicine, etc, especially as drug delivery agents, tissue filling agent, enzymeembedding agent and artificial skin, because of their high moisturizing ability and high water absorption. It can be divided into two types according to their raw material source, natural hydrogels and synthetic hydrogels. Although natural hydrogels have better biocompatibility, biodegradability than synthetic hydrogels, synthetic hydrogel materials have relatively high mechanical properties that attract researchers’ eyes. In recent years, it has become a research hotpot to combine the benefits of two types. A lot of researches on modification of hydrogels have emerged one after another, and some progress has made. This paper reviews the researches, development, biological evaluation of synthetic hydrogels based on poly(ethylene glycol), poly(vinyl alcohol), and polyacrylamide. Peculiar attention is paid to the applications in tissue engineering.