（1.College of Energy and Mechanical Engineering, Shanghai University of Electric Power, Shanghai 200090, China） (2.Guangxi Key Laboratory of Non-Ferrous Metal and Special Materials Processing, Guangxi University， Nanning 530004, China)
Metal nanoclusters have become one of the most potential guest materials due to their wide applications in the fields of light, electricity, magnetism and catalysis. Compared with gold, silver and platinum nanoclusters, copper nanoclusters (Cu NCs) have attracted much attention due to their low cost, low toxicity, good biocompatibility and unique optical properties. They are widely used in biomedicine, environmental detection and other fields, and show good performance. They are an effective substitute for traditional fluorescent materials such as organic dyes and semiconductor quantum dots. The synthesis methods and fluorescence properties of Cu NCs were systematically described. After that, the application of Cu NCs in the field of biological detection and environmental detection is systematically introduced, and the main problems and opportunities in the research and application of Cu NCS in related fields are analyzed.