（1.School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070, China） (2.Sanya Science and Education Innovation Park, Wuhan University of Technology, Sanya 572000, China）
With the broader application of antibiotics, abusing of antibiotics is becoming increasingly serious, which is followed by dangerous drug resistance. Therefore, the development of new green and highly active antibacterial materials becomes more important. Semiconductor photocatalytic agents are rapidly developing and popular antibacterial materials in recent years, because of their low cost, simple synthesis process, excellent antibacterial activity and broad application potential. The principle of photocatalytic antibacterial is introduced, the specific application of semiconductor materials based photocatalyst antibacterial in the field of medicine is focused, including wound dressings and medical coatings, and three strategies to enhance the antibacterial properties are discussed in detail, namely, improving photocatalytic activity, joint antibacterial and biomimetic surface construction. The latest research progress of composite antibacterial materials is mainly introduced, such as titanium dioxide, zinc oxide and carbon nitride, ect. These will help to design efficient photocatalytic antibacterial materials for basic research and practical application.