1.Faculty of Materials Metallurgy and Chemistry, Jiangxi University of Science and Technology, Ganzhou 341000, China
2.Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China
3.University of Chinese Academy of Sciences, Beijing 100049, China
4. Northeast Electric Power University, Jilin 132012, China
Medical polyurethane material has become an outstanding carrier of drugs,antibacterial agents, and anti-inflammatory agents, due to its low cytotoxicity, good biocompatibility, excellent mechanical properties, and other excellent characteristics. However, traditional polyurethane materials are highly dependent on petroleum resources, and their synthetic route is unfavorable for green and sustainable development. Due to the lack of inherent antibacterial activity and appropriate wettability, polyurethane materials are prone to wound infection and excessive wetting in wound dressing applications. In addition,most researchers’wound evaluation is limited to small animal models (mice, rabbits, etc.), which hinders further research on material properties. In this paper, the development status and existing problems of medical polyurethane materials in wound dressings, are discussed and summarized,and different forms of polyurethane such as nanofibers, films, hydrogels, sponges,and foams are analyzed. Moreover, some development directions of medical polyurethane dressings are proposed, including biomass polyurethane, multifunctional polyurethane and bilayer scaffold, etc. This paper is expected to provide theoretical foundation for the development of polyurethane materials in the medical field.