The metallic material for dental applications is categorized as classⅡmedical devices by National Medical Products Administration. It is expected to possess good mechanical properties and excellent biocompatibility. In this paper, the application of Ti-13Nb-13Zr alloy in surgical implants is further extended to prosthodontics. The Ti-13Nb-13Zr alloy was fabricated by hot-forging, the influence of the heat treatment on the microstructure and mechanical properties was analyzed, the microstructures were investigated by metallographic microscope, the tensile properties were measured by using universal electronic tensile machine. The results show that solution treated sample at 750 ℃ for 0.5 h followed by water quenching has a low elastic modulus (49 GPa) and good mechanical properties: ultimate tensile strength is 710 MPa, yield strength is 471 MPa, and elongation is 25%. It could be used for fabricating removable partial denture. The aging treatment sample which was treated at 460 ℃ for 7 h by water quenching after solution treatment at 680 ℃ for 1 h have the highest mechanical strength: ultimate tensile strength is 982 MPa, yield strength is 815 MPa, and elongation is 12%, its comprehensive properties meet requirements of dental crown. It can be concluded that suitably heat treated Ti-13Nb-13Zr alloys have the relatively fine microstructures and a combination of low elastic modulus and excellent strength, it is a promising candidate for dental material.