Metal matrix composites, which are composed of a high-strength reinforced phase and metal matrix, have shown excellent potential for applications in a variety of fields due to their comprehensive performance. Compared with the conventional reinforced phase, graphene is a two-dimensional carbon nanomaterial consisting of carbon atoms in sp2 hybridized orbitals with an overall hexagonal honeycomb lattice, which has superior electrical, mechanical, thermal, and optical properties due to its unique structure. Graphenereinforced metal matrix composites have become a research hotspot in the field of advanced composites, and for metal matrix composites, their comprehensive performance is closely related to the structure and properties of the interface. Based on the recent researches on the microstructure and theory of the interface of graphene-reinforced metal matrix composites, this review summarizes the interface structure and mechanical properties of common graphene-reinforced metal matrix composites, as well as concludes the progress of computer simulation in analyzing the interface structure, interface bonding strength, and interface micro fracture mechanism, which provides a theoretical basis for the design and optimization of the interface of metal matrix composites.