To solve the problem of poor wear performance of titanium and its alloys, two Ti/WC composite coatings with different compositions were deposited on Ti6Al4V alloy substrate using high-pressure cold spraying. The tribological properties of the substrate and the coatings were tested by dry sliding friction wear test at room temperature, and the wear surfaces were observed and characterized by scanning electron microscopy (SEM) and Raman spectroscopy. The results showed that the wear rates of the composite coatings are reduced by one order of magnitude compared with that of the Ti6Al4V matrix (4.06×10-7 mm3/(N·m)), exhibiting excellent wear resistance. In addition, the increase of WC content in the coating improves the microhardness and the wear resistance of the coating. On the surface of the wear track, the friction film composed of TiO2, WO3 and WC fragments can effectively avoid the direct contact between the grinding ball and the coating, thus reducing the degree of wear. Therefore, the cold-sprayed Ti/WC composite coating has certain application prospects in titanium alloy wear protection.