文章信息/Info

Title:

 Research Progress of Mg�睟ased Alloys as Degradable��Biomedical Materials

作者:

 袁廣銀; 張佳; 丁文江

 （上海交通大學 輕合金精密成型國家工程研究中心，上海 200240）

Author(s):

 YUAN Guangyin;  ZHANG Jia;  DING Wenjiang

 （National Engineering Research Center of Light Alloy Net Forming, Shanghai Jiao Tong University, Shanghai 200240, China）

關鍵詞:

 ; 鎂合金; 生物可降解材料; 骨科內植物; 血管支架材料

文獻標志碼:

A

摘要:

    生物體內可降解吸收材料是生物材料發展的重要方向，由于金屬材料具有較好的強度和塑韌性，因此金屬基可降解吸收材料具有重要的臨床應用價值。鎂是所有金屬材料中生物力學性能與人體骨最接近的金屬材料，具有理想的生物力學相容性，因此，鎂合金作為可降解生物材料具有巨大的應用潛力。首先介紹了鎂基材料作為生物體內可降解植入材料的優點，然后簡要回顧了鎂基可降解生物材料的早期研究情況，同時系統地介紹和總結了目前的研究進展和遇到的挑戰，最后展望了鎂合金醫用材料的應用前景和發展方向。��

Abstract:

    Biodegradable absorbent material in vivo is an important direction for the development of biological materials; and metal based biodegradable absorbent materials are of vital clinical value since metal material has preferable strength and plastic toughness. As metal material with closest biomechanical properties to those of human bone, magnesium has ideal biomechanical compatibility and its alloys have great application potential as biodegradable materials therefore. The advantages of magnesium based alloys as biodegradable implants are presented first. Then the early research history about biomagnesium is briefly reviewed; and current research progress and facing challenges of biomagnesium are introduced and summarized meanwhile. Finally, the future directions and research priorities of medical degradable magnesium based biomaterials are discussed.