文章信息/Info

Title:

Micro/Nano Fabrication of Inorganic/Organic Composite Scaffold for Tissue Engineering

作者:

 仇志燁; 王江林; 周嬌嬌; 張勝民

 （華中科技大學(xué)先進(jìn)生物材料與組織工程研究中心，湖北 武漢 430074）

Author(s):

 QIU Zhiye;  WANG Jianglin;  ZHOU Jiaojiao;  ZHANG Shengmin

 (Advanced Biomaterials and Tissue Engineering Center,�� Huazhong University of Science and Technology, Wuhan 430074, China)

關(guān)鍵詞:

 ; 無機(jī)-有機(jī)復(fù)合材料; 組織工程支架; 微納制造; 數(shù)字化制造; 納米技術(shù)

文獻(xiàn)標(biāo)志碼:

A

摘要:

    無機(jī)-有機(jī)復(fù)合組織器官工程支架的微納制造是近年來興起的生物材料研究領(lǐng)域，相對傳統(tǒng)的生物材料與組織工程材料制造技術(shù)，微納制造整合了微納米技術(shù)、計算機(jī)輔助設(shè)計、數(shù)字化制造等先進(jìn)技術(shù)手段，為新型生物醫(yī)用材料的開發(fā)以及生物材料制造新技術(shù)、新設(shè)備的研發(fā)提供了新的技術(shù)路線。綜述了生物醫(yī)用材料、特別是組織器官工程與組織修復(fù)材料微納制造技術(shù)現(xiàn)狀及發(fā)展趨勢，主要內(nèi)容包括生物材料的微納米化及實現(xiàn)途徑、組織器官工程支架材料的數(shù)字化設(shè)計、組織器官工程支架材料的數(shù)字化制造新技術(shù)等，對我國組織器官工程（修復(fù)）材料數(shù)字化微納制造新技術(shù)的優(yōu)先發(fā)展領(lǐng)域提出了展望。

Abstract:

    Micro/nano fabrication of inorganic/organic composite scaffold for tissue engineering is a biomaterial research field arisen in recent years. Compared to conventional fabrication technique for biomaterials and tissue engineering materials, micro/nano fabrication, which has been integrated with advanced techniques such as micron/nano technology, computer aided design and digital manufacturing, provides new technical routes for the development of novel biomedical materials. Current situation and developing trends of biomedical materials, especially micro/nano fabrication technique of tissue engineering and tissue repair materials, are reviewed, mainly including realizations and approaches of micro/nano�瞫ize biomaterials, digital design of tissue engineering scaffolds, as well as new techniques for digital manufacturing of tissue engineering scaffolds. Moreover, a strategic outlook is proposed for priority areas for development in new techniques of digital micro/nano fabrication of tissue engineering (repair) materials in China.