«上一篇/Previous Article|本期目錄/Table of Contents|下一篇/Next Article»

j.issn.1674-3962.2014.03.05]
點擊復制

印刷電子技術在生物傳感器中的應用()

分享到：

中國材料進展[ISSN:1674-3962/CN:61-1473/TG]

卷:
期數:: 2014年第3期

頁碼:: 029-36

欄目:: 特約研究論文

出版日期:: 2014-03-30

文章信息/Info

Title:: Application of Printing Electronic Technology in Biosensor

作者:: 李祥高; 吳憲; 王世榮; 天津大學化工學院，天津 300072

Author(s):: WU Xian; LI Xianggao; WANG Shirong; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072

關鍵詞:: 印刷電子; 生物傳感器; 導電油墨; 絲網印刷

DOI:: 10.7502/j.issn.1674-3962.2014.03.05

文獻標志碼:: A

摘要:: 生物傳感技術是生物學、化學、物理學和信息科學等的交叉學科，已發展成為一個十分活躍的研究領域。生物傳感器經過半個世紀的發展,開始在醫學、制藥、環境監測、國防和安全等許多領域得到應用。印刷電子技術是將現代印刷技術與微電子技術相結合來制造電子器件的前沿技術，是實現大批量制備生物傳感器的最佳方法之一。本文介紹了生物傳感器的研究歷程以及器件的結構、類型及傳感機理，重點總結了應用于不同生物傳感器的納米導電材料、介體物質、印刷油墨和作用原理的研究進展，以及絲網印刷、噴墨打印、微接觸印刷和卷對卷印刷等技術在制作生物傳感器方面各自的優勢和特點。

Abstract:: Biological sensing technology has become a very active research field because it is a new interdiscipline about biology, chemistry, physics and information science and technology. Biosensor has been widely used in many areas such as medical science, pharmacy, environmental monitoring, defense and security after half a century of development. Printedelectronic technology is a frontier technology of the hybrid of modern printing technology and microelectronic technique, and is one of the best manners to fabricate biological sensors in industry scale. In this paper, the research progress of biosensor and its structure, type and sensing mechanism is introduced, the electrically conductive nano-materials, mediators, printing ink and action principle are summarized in different biosensors, the especially the application advantages and characteristics of screen printing, ink-jet printing, micro-contact printing and roll-to-roll printing in the preparation of biosensors.

參考文獻/References:

[1] Ahmet K, Esma A, Yeliz K. Biosensors and Their Principles [EB/OL]. (2008)[2014].www.intechopen.com.

[2] Iqbal M A, Gupta S G, Hussaini S S. A Review on Electrochemical Biosensors: Principles and Applications[J]. Advances in Bioresearch ,2012, 3(4):158-164.

[3] Anthony P.F.T. Biosensors: sense and sensibility [J]. Chemical Society Reviews, 2013,42:3184-3196.

[4] Setti L, Fraleoni-Morgera A, Ballarin B, et al. An amperometric glucose biosensor prototype fabricated by thermal inkjet printing [J]. Biosensors and Bioelectronics, 2005, 20(10): 2019-2026.

[5] Liu H C, Tsai C C, Wang G J. Glucose biosensors based on a gold nanodendrite modified screen-printed electrode [J]. Nanotechnology 2013, 24(21): 215101.

[6] Nasri Z, Shams E. A glucose biosensor based on direct electron transfer of glucose oxidase immobilized onto glassy carbon electrode modified with nitrophenyl diazonium salt [J]. Electrochimica Acta, 2013, 112: 640-647.

[7] Tang H, Yan F, Lin P, et al. Highly Sensitive Glucose Biosensors Based on Organic Electrochemical Transistors Using Platinum Gate Electrodes Modified with Enzyme and Nanomaterials [J]. Advanced Functional Materials, 2011, 21(12): 2264-2272.

[8] Chappell P H. Making sense of artificial hands [J]. J Med Eng Technol, 2011, 35(1): 1-18.

[9] Camacho C, Matías J C, Chico B, et al. Amperometric Biosensor for Hydrogen Peroxide, Using Supramolecularly Immobilized Horseradish Peroxidase on the β-Cyclodextrin-Coated Gold Electrode [J]. Electroanalysis, 2007, 19(24): 2538-2542.

[10] Hideshima S, Hinou H, Ebihara D, et al. Attomolar Detection of Influenza A Virus Hemagglutinin Human H1 and Avian H5 Using Glycan-Blotted Field Effect Transistor Biosensor [J]. Analytical Chemistry, 2013, 85(12): 5641-5644.

[11] Keow C M, Bakar F A, Salleh A B, et al. Screen-printed histamine biosensors fabricated from the entrapment of diamine oxidase in a photocured poly (HEMA) film [J]. Int J Electrochem Sci, 2012, 7: 4702--4715.

[12] Piermarini S, Volpe G, Esti, M, et al. Real time monitoring of alcoholic fermentation with low-cost amperometric biosensors [J]. Food Chemistry, 2011, 127(2): 749-754.

[13] Lee S, Fang H, Chen W. Amperometric glucose biosensor based on screen-printed carbon electrodes mediated with hexacyanoferrate–chitosan oligomers mixture [J]. Sensors and Actuators B: Chemical, 2006, 117(1): 236-243.

[14] Ohfuji K, Sato N, Hamada-Sato N, et al. Construction of a glucose sensor based on a screen-printed electrode and a novel mediator pyocyanin from Pseudomonas aeruginosa [J]. Biosensors and Bioelectronics, 2004, 19(10): 1237-1244.

[15] Pemberton R M, Cox T, Tuffin R, et al. Microfabricated glucose biosensor for culture well operation [J]. Biosensors and Bioelectronics, 2013, 42: 668-677.

[16] Albanese D, Matteo D M, Alessio C. Screen printed biosensors for detection of nitrates in drinking water [J]. Computer Aided Chemical Engineering, 2010, 28: 283-288.

[17] Wcis?o M, Compagnone D, Trojanowicz M. Enantioselective screen-printed amperometric biosensor for the determination of [J] d-amino acids. Bioelectrochemistry, 2007, 71(1): 91-98.

[18] Román L D T, Alonso-Lomillo M A, Domínguez-Renedo O, et al. GADH screen-printed biosensor for gluconic acid determination in wine samples [J]. Sensors and Actuators B: Chemical, 2014, 192: 56-59.

[19] Hirst N A, Hazelwood L D, Jayne D G, et al. An amperometric lactate biosensor using H2O2 reduction via a Prussian Blue impregnated poly(ethyleneimine) surface on screen printed carbon electrodes to detect anastomotic leak and sepsis [J]. Sensors and Actuators B: Chemical, 2013, 186: 674-680.

[20] Chen P, Peng Y, He M, et al. Sensitive Electrochemical Detection of Creatinine at Disposable Screen-Printed Carbon Electrode Mixed with Ferrocenemethanol [J]. International Journal of Electrochemical Science, 2013, 8:8931-8939.

[21] Liu S, Guo X. Carbon nanomaterials field-effect-transistor-based biosensors [J]. NPG Asia Materials, 2012, 4(8): e23.

[22] Ilkhani H, Arvand M, Ganjali M R, et al. Nanostructured Screen Printed Graphite Electrode for the Development of a Novel Electrochemical Genosensor [J]. Electroanalysis, 2013, 25(2): 507-514.

[23] Yang X, Xiao F B, Lin H W, et al. A novel H2O2 biosensor based on Fe3O4–Au magnetic nanoparticles coated horseradish peroxidase and graphene sheets–Nafion film modified screen-printed carbon electrode [J]. Electrochimica Acta, 2013, 109: 750-755.

[24] Queirós R B, Guedes A, Marques P V S, et al. Recycling old screen-printed electrodes with newly designed plastic antibodies on the wall of carbon nanotubes as sensory element for in situ detection of bacterial toxins in water [J]. Sensors and Actuators B: Chemical, 2013, 189: 21-29.

[25] Alvarado-Gámez A L, Alonso-Lomillo M A, Domínguez-Renedo O, et al. Vanadium determination in water using alkaline phosphatase based screen-printed carbon electrodes modified with gold nanoparticles [J]. Journal of Electroanalytical Chemistry, 2013, 693: 51-55.

[26] Ahmad R, Vaseem M, Tripathy N, et al. Wide Linear-Range Detecting Nonenzymatic Glucose Biosensor Based on CuO Nanoparticles Inkjet-Printed on Electrodes [J]. Analytical Chemistry, 2013, 85(21): 10448-10454.

[27] Ekabutr P, Chailapakul O, Supaphol P. Modification of disposable screen-printed carbon electrode surfaces with conductive electrospun nanofibers for biosensor applications [J]. Journal of Applied Polymer Science, 2013,3885-3893.

[28] Phongphut A, Sriprachuabwong C, Wisitsoraat A, et al. A disposable amperometric biosensor based on inkjet-printed Au/PEDOT-PSS nanocomposite for triglyceride determination [J]. Sensors and Actuators B: Chemical, 2013, 178: 501-507.

[29] Karuwan C, Sriprachuabwong C, Wisitsoraat A, et al. Inkjet-printed graphene-poly(3,4-ethylenedioxythiophene):poly(styrene-sulfonate) modified on screen printed carbon electrode for electrochemical sensing of salbutamol [J]. Sensors and Actuators B: Chemical, 2012, 161(1): 549-555.

[30] Phongphut A, Sriprachuabwong C, Wisitsoraat A, et al. A disposable amperometric biosensor based on inkjet-printed Au/PEDOT-PSS nanocomposite for triglyceride determination [J]. Sensors and Actuators B: Chemical, 2013, 178: 501-507.

[31] Wagner M, Lisak G, Ivaska A, et al. Durable PEDOT:PSS films obtained from modified water-based inks for electrochemical sensors. Sensors and Actuators B: Chemical, 2013, 181: 694-701.

[32] Longinotti G, Lloret P, Ybarra G, et al. Screen-printed electrochemical biosensors based on magnetic core-shell nanoparticles[EB/OL].(2008)[ 2014].www.google.com.

[33] Bettazzi F, Enayati L, Sánchez I C, et al. Electrochemical bioassay for the detection of TNF-α using magnetic beads and disposable screen-printed array of electrodes [J]. Bioanalysis, 2013, 5(1): 11-19.

[34] Ricci F, Amine A, Palleschi G, et al. Prussian Blue based screen printed biosensors with improved characteristics of long-term lifetime and pH stability [J]. Biosens Bioelectron, 2003, 18(2-3): 165-74.

[35] Lee D H, Choi J S, Chae H, et al. Screen-printed white OLED based on polystyrene as a host polymer [J]. Current Applied Physics, 2009, 9(1): 161-164.