文章信息/Info

Title:

Effect and Hazard of Common Metal Elements on Human Body

文章編號:

1674-3962(2020)12-0934-11

作者:

李爭顯1; 2; 李偉2; LEI Jiajun3; LI Qianyu4; 劉林濤1; 周廉1

（1. 西北有色金屬研究院，陜西 西安 710016）（2. 西安建筑科技大學(xué)，陜西 西安 710055）（3. University of Florida, Florida Gainesville 32611, USA）（4. Arizona State University, Arizona Tempe 85281,USA）

Author(s):

LI Zhengxian1; 2;  LI Wei2;  LEI Jiajun3;  LI Qianyu4;  LIU Lintao1;  ZHOU Lian1

(1. Northwest Institute for Non-ferrous Metal Research, Xi’an 710016, China) (2. Xi’an University of Architecture and Technology, Xi’an 710055, China) (3. University of Florida, Gainesville 32611, USA) (4. Arizona State University, Tempe 85281,USA）

關(guān)鍵詞:

金屬元素; 毒性; 人體攝入; 健康

Keywords:

metal elements;  toxicity;  human intake;  health

分類號:

R318.08

DOI:

10.7502/j.issn.1674-3962.202003018

文獻(xiàn)標(biāo)志碼:

A

摘要:

金屬元素與人類生活息息相關(guān)，金屬的應(yīng)用推動了人類生活的發(fā)展，同時也給人體帶來一些副作用。金屬元素中有的是人體必需元素，有的則是非必需元素，必需元素在人體內(nèi)的平衡被打破（缺失、過量），也會對人體健康產(chǎn)生不利影響；而非必需元素，特別是一些重金屬元素往往對人體有毒性，甚至?xí)�產(chǎn)生致癌作用。綜述了鉛、汞、鎘、鉻、鋁、銅、鎳、鋅、鐵、鈷、鈦、鋇、錳13種金屬對環(huán)境和人類健康的影響，介紹了金屬元素的來源和人類攝入金屬元素的方式。進(jìn)一步闡述了金屬元素的毒性機(jī)制，如刺激細(xì)胞氧化應(yīng)激、抑制DNA表達(dá)、誘發(fā)突變導(dǎo)致癌細(xì)胞的產(chǎn)生和增殖等，旨在通過闡明金屬元素與人體健康之間的關(guān)系，加強(qiáng)人類對金屬元素的自我防范意識。

Abstract:

Metal elements are closely related to human life. The applications of metals promote the development of human life, and also bring some side effects to our human body. In our daily life, some metal elements are essential elements for the human body, but others are not. The intake of nonessential elements, especially some heavy metal elements which are often toxic to the human body, may cause diseases or even carcinogenesis. While, the broken balance of essential elements (missing, excessive) also have adverse effects on human health. In this study, the effects of 13 metal elements, including lead, mercury, cadmium, chromium, aluminum, copper, nickel, zinc, iron, cobalt, titanium, barium, manganese, on the environment and human health are reported. Furthermore, the toxic mechanism of metal elements, such as stimulating oxidative stress of cells, inhibiting DNA expression, inducing mutations, and leading to the generation and reproduction of cancer cells, are further expounded. The aim is to elucidate the relationship between metal elements and human health, and strengthen the human self-defense awareness on metal elements.