文章信息/Info

Title:

Research Progress on Materials and Devices Related to Virus Enrichment

文章編號:

1674-3962(2025)07-0673-11

作者:

張戈; 敖青; 周雪雁; 丁功濤; 王子凡; TEOW Yeit Haan; MOHD Shaiful Sajab; 馬忠仁; 李志強; 趙蕾

1. 西北民族大學 生物醫學研究中心，甘肅 蘭州 730030 2. 西北民族大學生命科學與工程學院，甘肅 蘭州 730030 等

Author(s):

ZHANG Ge;  AO Qing;  ZHOU Xueyan;  DING Gongtao;  WANG Zifan;  TEOW Yeit Haan;  MOHD Shaiful Sajab;  MA Zhongren;  LI Zhiqiang;  ZHAO Lei

1. Biomedical Research Center, Northwest Minzu University, Lanzhou 730030, China 2. School of Life Sciences and Engineering, Northwest Minzu University, Lanzhou 730030, China et al.

關鍵詞:

病毒富集; 材料及裝置; 病毒表面電荷; 特異性蛋白; 病毒尺寸

Keywords:

virus enrichment;  materials and devices;  virus surface charge;  specific proteins;  virus size

分類號:

Q819;TB383

DOI:

10.7502/j.issn.1674-3962.202407009

文獻標志碼:

A

摘要:

環境中存在的各種致病病毒對人類的健康造成了極大的危害。高效、快速的病毒富集技術對于早期病毒的診斷和疾病預警、防控具有重要意義。然而，目前有關病毒富集的綜述大多側重于病毒的富集方法，對材料及裝置的研究較少。從病毒的電荷特性、生化特性及尺寸等方面闡述了富集病毒的相關材料及裝置，涉及冠狀病毒、流感病毒、諾如病毒等。此外，結合實例對納米材料在病毒富集中的應用潛力，尤其在空氣傳播病毒檢測中的有效性進行了說明。同時，探討了基于其他性質的病毒富集材料和裝置，如通過蒸發去除溶劑達到富集目的的方法。最后，探討了微流控芯片在病毒富集領域的技術優化和應用前景，旨在為后續研究提供理論參考。

Abstract:

The various pathogenic viruses present in the environment pose a great threat to human health. Efficient and rapid virus enrichment technology is of great importance for early virus diagnosis, disease warning, prevention and control.However, current reviews on virus enrichment mostly focus on methods, with less research on materials and devices. This review elaborates on the relevant materials and devices for enriching viruses from the aspects of their charge characteristics, biochemical characteristics and size, involving coronaviruses, influenza viruses, norovirus, etc. This review introduces the potential application of nanomaterials in virus enrichment and demonstrates their effectiveness in detecting airborne viruses through examples.Meanwhile,we explore virus enrichment materials and devices based on other properties, such as methods of achieving enrichment by evaporating solvents. Finally, the technical optimization and application prospects of microfluidic chips in the field of virus enrichment are discussed,aiming to provide theoretical references for subsequent studies.